Effects of α-endorphin, β-endorphin and (des-tyr1)-γ-endorphin on α-MPT-induced catecholamine disappearance in discrete regions of the rat brain
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We summarize here our new discovery that the endogenous opioid peptide β-endorphin (BEP), by virtue of reducing body stress and maintaining active immune system, as well as, balancing the levels of pro-inflammatory and anti-inflammatory cytokines, destroys tumor cells and stops them from being transformed into metastatic cancer cells.
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Continuous labeling and pulse-chase techniques were employed to study the synthesis and secretion of multiple forms of immunoreactive ,f?-endorphin by cultured dispersed rat anterior lobe cells and intact neurointermediate pituitary lobe. Cell and medium extract immunoreactive pendorphin (specific immunoprecipitation and radioimmunoassay) exhibiting a K,, similar to authentic ,&endorphin upon g...
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ژورنال
عنوان ژورنال: Brain Research
سال: 1979
ISSN: 0006-8993
DOI: 10.1016/0006-8993(79)90492-x